Sex differentiation
Summary
Description
The first sequence animates the determination of sex at the moment of fertilization. The penetration of a gynespermatozoon and an androspermatozoon into secondary oocytes resulting in a female and a male are shown.
The next sequence shows the position of the sex-determining region (SRY) in the Y chromosome. A male embryo at the beginning of the 5th week explains the importance of the Y chromosome for the development of the testis .... (more)
The first sequence animates the determination of sex at the moment of fertilization. The penetration of a gynespermatozoon and an androspermatozoon into secondary oocytes resulting in a female and a male are shown.
The next sequence shows the position of the sex-determining region (SRY) in the Y chromosome. A male embryo at the beginning of the 5th week explains the importance of the Y chromosome for the development of the testis . On the diagram, the genital and the mesonephric ridges are indicated along with the mesonephric duct, mesonephric tubule, renal corpuscle and mesenchymal cells with transcripts of SRY gene. In the next sequence, the proliferation of the celomic epithelium is animated. Then, early in the 6th week, the gonocytes arrive through the mesentery. Finally, the gonocytes invade the testis cords, and the precursors of the Leydig cells settle between the testis cords. One week later, the rete testic cords connect with the mesonephric tubule, and the renal corpuscle is obliterated. The next sequence shows the secretory role of the Sertoli cells under the action of the SRY during the course of the 8th week. The last sequence animates the formation of the tunica albuginea, differentiation of the Leydig cell and myofibroblasts, and the obliteration of the paramesonephric duct in an 8-week-old fetus.
The next sequences illustrate that ovaries develop in the absence of the Y chromosome. The diagram shows the future genital ridge, containing mesenchymal cells without transcripts of SRY gene, in a 5-week-old female embryo. The next sequence animates the gonocytes invading the primitive sex cords in a 6-week-old female embryo. One week later, the rete ovarii form. During the 8th week, the primitive sex cords split into future primordial follicles. The nephron, mesonephric duct and rete ovarii start to degenerate, while the tunica albuginea begins to form. Finally, in an 8-week-old female embryo, the paramesonephric duct and primordial follicles develop, surrounded by the theca interna cells. The interstitial cells appear near the former rete ovarii.
A special diagram shows the homologies in the gonads.
(This animation is essential for students of medicine, veterinary medicine, and biology as well as for departments of anatomy, histology, embryology, and cell biology; it is also recommended for students of stomatology; departments or clinics of genetics, obstetrics, and gynecology; fertility or reproductive research institutes; and schools for midwives.)
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Details
3.5MB in size
209 pictures
6 chapters
17 legend panels
Version 1.0
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Amnion, Aortic arches, Blood and blood vessels, Body cavities, Central nervous system, Chromosomal anomalies, Cleavage, Cloaca, Cycles, Deciduae, Descent of sexual organs, Diaphragm, Digestive system, Ear, Embryology beginning, Embryonic circulation, Endochondral ossification, Endocrine glands, External genitalia, Eye, Face, Fertilization, Fetal circulation, Gametogenesis, Gastrulation, Gonads, Heart, Implantation, Integumentary system, Kidney, Liver, Long bone growth in diameter, Lymphatic system, Membranous ossification, Mesoderm, Myogenesis, Nerve fibres, Notochord, Olfactory, Pancreas, Pericardial reflexions, Pharyngeal arches, Placenta, Prostate, Respiratory system, Secondary ossification, Sex differentiation, Skeleton, Somites, Teeth, Tongue, Twins, Umbilical cord, Urinary bladder, Uterus during pregnancy, Veins |
Structure
View the structure of the Sex differentiation animation without thumbnails:
- SEX DIFFERENTIATION
Animated scheme - Position of the sex-determining region (SRY) in the Y chromosome
- Y chromosome is essential for the development of the testes
- In the absence of the Y chromosome the ovaries develop
- Homologies in the gonads
- Differentiating gonads
- THE END
RELATED TOPICS are covered in the following animations:
Chromosomal anomalies, Cloaca, External genitalia, Fertilization, Gametogenesis, Gonads, Kidney.
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- Amnion
- Aortic arches
- Blood and blood vessels
- Body cavities
- Central nervous system
- Chromosomal anomalies
- Cleavage
- Cloaca
- Cycles
- Deciduae
- Descent of sexual organs
- Diaphragm
- Digestive system
- Ear
- Embryology beginning
- Embryonic circulation
- Endochondral ossification
- Endocrine glands
- External genitalia
- Eye
- Face
- Fertilization
- Fetal circulation
- Gametogenesis
- Gastrulation
- Gonads
- Heart
- Implantation
- Integumentary system
- Kidney
- Liver
- Long bone growth in diameter
- Lymphatic system
- Membranous ossification
- Mesoderm
- Myogenesis
- Nerve fibres
- Notochord
- Olfactory
- Pancreas
- Pericardial reflexions
- Pharyngeal arches
- Placenta
- Prostate
- Respiratory system
- Secondary ossification
- Sex differentiation
- Skeleton
- Somites
- Teeth
- Tongue
- Twins
- Umbilical cord
- Urinary bladder
- Uterus during pregnancy
- Veins